Evaluation of cord blood ischemia modified albumin in normal pregnancies and pre-eclampsia.
Hypertens Pregnancy
; 34(2): 204-8, 2015 May.
Article
in En
| MEDLINE
| ID: mdl-25775261
OBJECTIVE: Pre-eclampsia is associated with ischemia and increased oxidative stress, which may lead to modification of plasma albumin to ischemia modified albumin (IMA). METHODS: IMA levels were estimated in cord blood of 30 newborns born to pre-eclamptic mothers and compared with 30 normal newborns. IMA was estimated colorimetrically and the results were compared statistically. RESULTS: The levels of IMA were found to be significantly higher (p < 0.001) in newborns born to pre-eclamptic mothers (0.835 ± 0.02 ABSU) as compared to those born to normal mothers (0.325 ± 0.01 ABSU). CONCLUSION: IMA may act as a marker of ischemia and oxidative stress in newborns delivered to pre-eclamptic mothers.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pre-Eclampsia
/
Pregnancy
/
Fetal Blood
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Newborn
Language:
En
Journal:
Hypertens Pregnancy
Journal subject:
ANGIOLOGIA
/
OBSTETRICIA
Year:
2015
Document type:
Article
Country of publication: