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A non-human primate model for investigating drug-induced risk of orthostatic hypotension and sympathetic dysfunction: Preclinical correlate to a clinical test.
Bhatt, Siddhartha; Foote, Stephen; Smith, Andrew; Butler, Paul; Steidl-Nichols, Jill.
Affiliation
  • Bhatt S; Global Safety Pharmacology, Pfizer Worldwide Research and Development, Groton, CT, USA. Electronic address: Siddhartha.Bhatt@pfizer.com.
  • Foote S; Global Safety Pharmacology, Pfizer Worldwide Research and Development, Groton, CT, USA.
  • Smith A; Global Safety Pharmacology, Pfizer Worldwide Research and Development, Groton, CT, USA.
  • Butler P; Global Safety Pharmacology, Pfizer Worldwide Research and Development, Groton, CT, USA.
  • Steidl-Nichols J; Global Safety Pharmacology, Pfizer Worldwide Research and Development, Groton, CT, USA.
J Pharmacol Toxicol Methods ; 73: 49-55, 2015.
Article in En | MEDLINE | ID: mdl-25837852
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sympathetic Nervous System / Blood Pressure / Hypotension, Orthostatic / Antihypertensive Agents Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: J Pharmacol Toxicol Methods Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2015 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sympathetic Nervous System / Blood Pressure / Hypotension, Orthostatic / Antihypertensive Agents Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: J Pharmacol Toxicol Methods Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2015 Document type: Article Country of publication: