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Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity.
Xiang, Wei; Menges, Stefanie; Schlachetzki, Johannes Cm; Meixner, Holger; Hoffmann, Anna-Carin; Schlötzer-Schrehardt, Ursula; Becker, Cord-Michael; Winkler, Jürgen; Klucken, Jochen.
Affiliation
  • Xiang W; Institute of Biochemistry (Emil-Fischer-Center), Friedrich-Alexander-University of Erlangen-Nürnberg (FAU), Fahrstraße 17, 91054, Erlangen, Germany. wei.xiang@fau.de.
  • Menges S; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany. stefanie.menges@uk-erlangen.de.
  • Schlachetzki JC; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany. johannes.schlachetzki@uk-erlangen.de.
  • Meixner H; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany. holger.meixner@uk-erlangen.de.
  • Hoffmann AC; Institute of Biochemistry (Emil-Fischer-Center), Friedrich-Alexander-University of Erlangen-Nürnberg (FAU), Fahrstraße 17, 91054, Erlangen, Germany. anna-carin.hoffmann@fau.de.
  • Schlötzer-Schrehardt U; Department of Ophthalmology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany. ursula.schloetzer-schrehardt@uk-erlangen.de.
  • Becker CM; Institute of Biochemistry (Emil-Fischer-Center), Friedrich-Alexander-University of Erlangen-Nürnberg (FAU), Fahrstraße 17, 91054, Erlangen, Germany. cord-michael.becker@fau.de.
  • Winkler J; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany. juergen.winkler@uk-erlangen.de.
  • Klucken J; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany. jochen.klucken@uk-erlangen.de.
Mol Neurodegener ; 10: 8, 2015 Mar 11.
Article in En | MEDLINE | ID: mdl-25886189
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Protein Processing, Post-Translational / Alpha-Synuclein / Histidine / Mutation Limits: Humans Language: En Journal: Mol Neurodegener Year: 2015 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Protein Processing, Post-Translational / Alpha-Synuclein / Histidine / Mutation Limits: Humans Language: En Journal: Mol Neurodegener Year: 2015 Document type: Article Affiliation country: Country of publication: