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Population Pharmacokinetic and Pharmacodynamic Modeling and Effects on Platelet Counts of Different Dosages of Eltrombopag in Chinese Patients With Chronic Primary Immune Thrombocytopenia.
Wu, Kai; Thapar, Mita; Farrell, Colm; Hayes, Siobhan; Guo, Haiyi; Hou, Ming; Zhang, Jianping.
Affiliation
  • Wu K; Department of Clinical Pharmacology, Modeling and Simulation, GlaxoSmithKline, Shanghai, China.
  • Thapar M; ICON Development Solutions, Marlow, United Kingdom.
  • Farrell C; ICON Development Solutions, Marlow, United Kingdom.
  • Hayes S; ICON Development Solutions, Marlow, United Kingdom.
  • Guo H; China Medicine Development, GlaxoSmithKline, Shanghai, China.
  • Hou M; Department of Hematology, Qilu Hospital, Shandong University, Shandong, China. Electronic address: houming@medmail.com.cn.
  • Zhang J; Department of Clinical Pharmacology, Modeling and Simulation, GlaxoSmithKline, Research Triangle Park, North Carolina.
Clin Ther ; 37(7): 1382-95, 2015 Jul 01.
Article in En | MEDLINE | ID: mdl-25929594
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Benzoates / Blood Platelets / Purpura, Thrombocytopenic, Idiopathic / Receptors, Thrombopoietin / Hydrazines Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Clin Ther Year: 2015 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Benzoates / Blood Platelets / Purpura, Thrombocytopenic, Idiopathic / Receptors, Thrombopoietin / Hydrazines Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Clin Ther Year: 2015 Document type: Article Affiliation country: