Your browser doesn't support javascript.
loading
Excluding T Cells: Is ß-Catenin the Full Story?
Hu-Lieskovan, Siwen; Homet Moreno, Blanca; Ribas, Antoni.
Affiliation
  • Hu-Lieskovan S; Division of Hematology-Oncology, Department of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center (JCCC) at UCLA, Los Angeles, CA 90095, USA.
  • Homet Moreno B; Division of Hematology-Oncology, Department of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA.
  • Ribas A; Division of Hematology-Oncology, Department of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA; Department of Surgery, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA; Department of Medical and Molecular Pharmacology, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center (JCCC) at UCLA, Los Angeles, CA 90095, USA. Electronic address: aribas@mednet.ucla.edu.
Cancer Cell ; 27(6): 749-50, 2015 Jun 08.
Article in En | MEDLINE | ID: mdl-26058073
Spranger and colleagues reported recently in Nature an inverse relationship between melanoma intrinsic ß-catenin signaling and intratumoral T cell infiltration, providing an explanation for potential mechanisms of T cell exclusion. Further insights are needed into the mechanisms leading to a lack of T cell infiltration of cancers and primary immune resistance.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Signal Transduction / Beta Catenin / Tumor Microenvironment / Melanoma Limits: Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2015 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Signal Transduction / Beta Catenin / Tumor Microenvironment / Melanoma Limits: Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2015 Document type: Article Affiliation country: Country of publication: