Gastrointestinal symptoms are closely associated with depression in iron deficiency anemia: a comparative study.
Ann Saudi Med
; 35(1): 31-5, 2015.
Article
in En
| MEDLINE
| ID: mdl-26142935
ABSTRACT
BACKGROUND AND OBJECTIVES:
Until now, very few studies evaluated the association between gastrointestinal and psychiatric symptoms in iron deficiency anemia (IDA). The study investigated the frequency of functional dyspepsia (FD) in IDA patients and determined its association with depression and somatization. DESIGN AND SETTINGS The study was conducted at the Hematology Department of Trakya University Medical Faculty, which is a tertiary referral center in northwestern Turkey. It was a case-control study. MATERIALS ANDMETHODS:
A total of 125 consecutive IDA patients and 57 healthy control subjects were included. Patients and controls were questioned about the severity of their gastrointestinal system (GIS)-related symptoms and the presence of constipation and associated symptoms using a visual analog scale. In addition, IDA patients were administered a validated depression scale (Beck Depression Inventory, BDI) and somatization symptoms checklist.RESULTS:
IDA patients had more frequent self-reported constipation compared with controls (56% vs 22.8%, P < .001). The mean scores of bloating, dyspepsia, and constipation-related quality of life (QoL) disturbance were significantly higher in the IDA group than in the control group (all P values.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anemia, Iron-Deficiency
/
Depression
/
Dyspepsia
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Qualitative_research
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Ann Saudi Med
Journal subject:
MEDICINA
Year:
2015
Document type:
Article