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Modulation of disulfide dual ENKephalinase inhibitors (DENKIs) activity by a transient N-protection for pain alleviation by oral route.
Poras, Hervé; Bonnard, Elisabeth; Fournié-Zaluski, Marie-Claude; Roques, Bernard P.
Affiliation
  • Poras H; Pharmaleads, Paris BioPark, 11 rue Watt, 75013 Paris, France. Electronic address: herve.poras@pharmaleads.com.
  • Bonnard E; Pharmaleads, Paris BioPark, 11 rue Watt, 75013 Paris, France. Electronic address: elisabeth.bonnard@pharmaleads.com.
  • Fournié-Zaluski MC; Pharmaleads, Paris BioPark, 11 rue Watt, 75013 Paris, France. Electronic address: marie-claude.fournie-zaluski@pharmaleads.com.
  • Roques BP; Pharmaleads, Paris BioPark, 11 rue Watt, 75013 Paris, France; Université Paris-Descartes, 4 Avenue de l'Observatoire, 75006 Paris, France. Electronic address: bernard.roques@pharmaleads.com.
Eur J Med Chem ; 102: 58-67, 2015 Sep 18.
Article in En | MEDLINE | ID: mdl-26241877
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Protease Inhibitors / Neprilysin / Disulfides / Analgesics Limits: Animals Language: En Journal: Eur J Med Chem Year: 2015 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Protease Inhibitors / Neprilysin / Disulfides / Analgesics Limits: Animals Language: En Journal: Eur J Med Chem Year: 2015 Document type: Article Country of publication: