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Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins.
Kaya, Alaattin; Gerashchenko, Maxim V; Seim, Inge; Labarre, Jean; Toledano, Michel B; Gladyshev, Vadim N.
Affiliation
  • Kaya A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115;
  • Gerashchenko MV; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115;
  • Seim I; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115;
  • Labarre J; Oxidative Stress and Cancer, Institut de Biologie et Technologie-Saclay, FRE3377 Commisariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, CEA-Saclay, F-91191 Gif Sur Yvette, France.
  • Toledano MB; Oxidative Stress and Cancer, Institut de Biologie et Technologie-Saclay, FRE3377 Commisariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, CEA-Saclay, F-91191 Gif Sur Yvette, France.
  • Gladyshev VN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; vgladyshev@rics.bwh.harvard.edu.
Proc Natl Acad Sci U S A ; 112(34): 10685-90, 2015 Aug 25.
Article in En | MEDLINE | ID: mdl-26261310

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae / Adaptation, Physiological / Chromosomes, Fungal / Chromosome Deletion / Saccharomyces cerevisiae Proteins / Mitochondrial Proteins / Electron Transport / Aneuploidy Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae / Adaptation, Physiological / Chromosomes, Fungal / Chromosome Deletion / Saccharomyces cerevisiae Proteins / Mitochondrial Proteins / Electron Transport / Aneuploidy Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Document type: Article