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Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.
Khiati, Salim; Baechler, Simone A; Factor, Valentina M; Zhang, Hongliang; Huang, Shar-yin N; Dalla Rosa, Ilaria; Sourbier, Carole; Neckers, Leonard; Thorgeirsson, Snorri S; Pommier, Yves.
Affiliation
  • Khiati S; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Baechler SA; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Factor VM; Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Zhang H; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Huang SY; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Dalla Rosa I; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Sourbier C; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
  • Neckers L; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
  • Thorgeirsson SS; Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Pommier Y; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; pommier@nih.gov.
Proc Natl Acad Sci U S A ; 112(36): 11282-7, 2015 Sep 08.
Article in En | MEDLINE | ID: mdl-26305952
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / DNA Topoisomerases, Type I / Hepatocytes / Liver Regeneration Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / DNA Topoisomerases, Type I / Hepatocytes / Liver Regeneration Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Document type: Article Country of publication: