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Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting.
Meyer, Saskia; Nederend, Maaike; Jansen, J H Marco; Reiding, Karli R; Jacobino, Shamir R; Meeldijk, Jan; Bovenschen, Niels; Wuhrer, Manfred; Valerius, Thomas; Ubink, Ruud; Boross, Peter; Rouwendal, Gerard; Leusen, Jeanette H W.
Affiliation
  • Meyer S; a Laboratory of Translational Immunology; UMC Utrecht ; Utrecht , The Netherlands.
  • Nederend M; a Laboratory of Translational Immunology; UMC Utrecht ; Utrecht , The Netherlands.
  • Jansen JH; a Laboratory of Translational Immunology; UMC Utrecht ; Utrecht , The Netherlands.
  • Reiding KR; b Center for Proteomics and Metabolomics; Leiden University Medical Center ; Leiden , The Netherlands.
  • Jacobino SR; a Laboratory of Translational Immunology; UMC Utrecht ; Utrecht , The Netherlands.
  • Meeldijk J; a Laboratory of Translational Immunology; UMC Utrecht ; Utrecht , The Netherlands.
  • Bovenschen N; a Laboratory of Translational Immunology; UMC Utrecht ; Utrecht , The Netherlands.
  • Wuhrer M; c Department of Pathology ; UMC Utrecht ; Utrecht , The Netherlands.
  • Valerius T; b Center for Proteomics and Metabolomics; Leiden University Medical Center ; Leiden , The Netherlands.
  • Ubink R; d Division of Stem Cell Transplantation and Immunotherapy ; Department of Internal Medicine II; Christian-Albrechts-University ; Kiel , Germany.
  • Boross P; e Synthon Biopharmaceuticals BV ; Nijmegen , The Netherlands.
  • Rouwendal G; a Laboratory of Translational Immunology; UMC Utrecht ; Utrecht , The Netherlands.
  • Leusen JH; e Synthon Biopharmaceuticals BV ; Nijmegen , The Netherlands.
MAbs ; 8(1): 87-98, 2016.
Article in En | MEDLINE | ID: mdl-26466856
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin A / Receptors, Fc / Histocompatibility Antigens Class I / Receptor, ErbB-2 / Trastuzumab / Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2016 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin A / Receptors, Fc / Histocompatibility Antigens Class I / Receptor, ErbB-2 / Trastuzumab / Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2016 Document type: Article Affiliation country: Country of publication: