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Use of 4ß-hydroxycholesterol in animal and human plasma samples as a biomarker for CYP3A induction.
Xue, Y-J; Hoffmann, Matthew; Tong, Zeen; Wu, Xinqun Irene; Vallejo, Martha; Melo, Brian; Ye, Ying; Thomas, Michael; Liu, Yong; Weiss, Daniel; Surapaneni, Sekhar.
Affiliation
  • Xue YJ; Drug Metabolism & Pharmacokinetics Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Hoffmann M; Drug Metabolism & Pharmacokinetics Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Tong Z; Drug Metabolism & Pharmacokinetics Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Wu XI; Drug Metabolism & Pharmacokinetics Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Vallejo M; Drug Metabolism & Pharmacokinetics Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Melo B; Drug Metabolism & Pharmacokinetics Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Ye Y; Clinical Pharmacology Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Thomas M; Clinical Pharmacology Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Liu Y; Clinical Pharmacology Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Weiss D; Clinical Pharmacology Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
  • Surapaneni S; Drug Metabolism & Pharmacokinetics Department, Celgene, 86 Morris Avenue, Summit, NJ 07901, USA.
Bioanalysis ; 8(3): 215-28, 2016 Feb.
Article in En | MEDLINE | ID: mdl-26805594
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Chemical Analysis / Cytochrome P-450 CYP3A / Hydroxycholesterols Limits: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: Bioanalysis Year: 2016 Document type: Article Affiliation country:
Fulltext
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Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Chemical Analysis / Cytochrome P-450 CYP3A / Hydroxycholesterols Limits: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: Bioanalysis Year: 2016 Document type: Article Affiliation country: