An autoimmune polyglandular syndrome complicated with celiac disease and autoimmune hepatitis.
Ann Hepatol
; 15(4): 588-91, 2016.
Article
in En
| MEDLINE
| ID: mdl-27236159
ABSTRACT
Autoimmune polyglandular syndrome (APS) is a combination of different autoimmune diseases. The close relationship between immune-mediated disorders makes it mandatory to perform serological screening periodically in order to avoid delayed diagnosis of additional autoimmune diseases. We studied a patient with type 1 diabetes (T1D) who later developed an autoimmune thyroid disease (ATD) and was referred to our hospital with a serious condition of his clinical status. The patient was suffering from an advance stage of celiac disease (CD), the delay in its diagnosis and in the establishment of a gluten-free dietled the patient to a severe proteincalorie malnutrition. Later, the patient developed an autoimmune hepatitis (AIH). We consider that clinical deterioration in patients with APS should alert physicians about the possible presence of other immune-mediated diseases. Periodic screening for autoantibodies would help to prevent delayed diagnosis and would improve patient's quality of life.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thyroiditis, Autoimmune
/
Celiac Disease
/
Polyendocrinopathies, Autoimmune
/
Protein-Energy Malnutrition
/
Hepatitis, Autoimmune
/
Diabetes Mellitus, Type 1
Type of study:
Diagnostic_studies
/
Etiology_studies
Aspects:
Patient_preference
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ann Hepatol
Journal subject:
GASTROENTEROLOGIA
Year:
2016
Document type:
Article
Affiliation country: