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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
Gormley, Padhraig; Anttila, Verneri; Winsvold, Bendik S; Palta, Priit; Esko, Tonu; Pers, Tune H; Farh, Kai-How; Cuenca-Leon, Ester; Muona, Mikko; Furlotte, Nicholas A; Kurth, Tobias; Ingason, Andres; McMahon, George; Ligthart, Lannie; Terwindt, Gisela M; Kallela, Mikko; Freilinger, Tobias M; Ran, Caroline; Gordon, Scott G; Stam, Anine H; Steinberg, Stacy; Borck, Guntram; Koiranen, Markku; Quaye, Lydia; Adams, Hieab H H; Lehtimäki, Terho; Sarin, Antti-Pekka; Wedenoja, Juho; Hinds, David A; Buring, Julie E; Schürks, Markus; Ridker, Paul M; Hrafnsdottir, Maria Gudlaug; Stefansson, Hreinn; Ring, Susan M; Hottenga, Jouke-Jan; Penninx, Brenda W J H; Färkkilä, Markus; Artto, Ville; Kaunisto, Mari; Vepsäläinen, Salli; Malik, Rainer; Heath, Andrew C; Madden, Pamela A F; Martin, Nicholas G; Montgomery, Grant W; Kurki, Mitja I; Kals, Mart; Mägi, Reedik; Pärn, Kalle.
Affiliation
  • Gormley P; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Anttila V; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Winsvold BS; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Palta P; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Esko T; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Pers TH; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Farh KH; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Cuenca-Leon E; FORMI, Oslo University Hospital, Oslo, Norway.
  • Muona M; Department of Neurology, Oslo University Hospital, Oslo, Norway.
  • Furlotte NA; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Kurth T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Ingason A; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • McMahon G; Estonian Genome Center, University of Tartu, Tartu, Estonia.
  • Ligthart L; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Terwindt GM; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Kallela M; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Freilinger TM; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Ran C; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Gordon SG; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Stam AH; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Steinberg S; Illumina, San Diego, California, USA.
  • Borck G; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Koiranen M; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Quaye L; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Adams HH; Pediatric Neurology, Vall d'Hebron Research Institute, Barcelona, Spain.
  • Lehtimäki T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Sarin AP; Folkhälsan Institute of Genetics, Helsinki, Finland.
  • Wedenoja J; Neuroscience Center, University of Helsinki, Helsinki, Finland.
  • Hinds DA; Molecular Neurology Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.
  • Buring JE; 23andMe, Inc., Mountain View, California, USA.
  • Schürks M; Institute of Public Health, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Hrafnsdottir MG; deCODE Genetics, Reykjavik, Iceland.
  • Stefansson H; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Ring SM; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
  • Hottenga JJ; Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands.
  • Penninx BW; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.
  • Färkkilä M; Department of Neurology and Epileptology, Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.
  • Artto V; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Kaunisto M; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Vepsäläinen S; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Malik R; Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands.
  • Heath AC; deCODE Genetics, Reykjavik, Iceland.
  • Madden PA; Institute of Human Genetics, Ulm University, Ulm, Germany.
  • Martin NG; Center for Life Course Epidemiology and Systems Medicine, University of Oulu, Oulu, Finland.
  • Montgomery GW; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Kurki MI; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Kals M; Department of Radiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Mägi R; Department of Clinical Chemistry, Fimlab Laboratories, School of Medicine, University of Tampere, Tampere, Finland.
  • Pärn K; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Nat Genet ; 48(8): 856-66, 2016 08.
Article in En | MEDLINE | ID: mdl-27322543
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Markers / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Genetic Loci / Migraine Disorders Type of study: Observational_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2016 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Markers / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Genetic Loci / Migraine Disorders Type of study: Observational_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2016 Document type: Article Affiliation country: Country of publication: