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Treatment with human, recombinant FSH improves sperm DNA fragmentation in idiopathic infertile men depending on the FSH receptor polymorphism p.N680S: a pharmacogenetic study.
Simoni, Manuela; Santi, Daniele; Negri, Luciano; Hoffmann, Ivan; Muratori, Monica; Baldi, Elisabetta; Cambi, Marta; Marcou, Marios; Greither, Thomas; Baraldi, Enrica; Tagliavini, Simonetta; Carra, Daniela; Lombardo, Francesco; Gandini, Loredana; Pallotti, Francesco; Krausz, Csilla; Rastrelli, Giulia; Ferlin, Alberto; Menegazzo, Massimo; Pignatti, Elisa; Linari, Francesca; Marino, Marco; Benaglia, Renzo; Levi-Setti, Paolo E; Behre, Hermann M.
Affiliation
  • Simoni M; Department of Biomedical, Metabolic and Neural Sciences, University of Modena & Reggio Emilia, Modena, Italy Azienda USL of Modena, Modena, Italy Center for Genomic Research, University of Modena & Reggio Emilia, Modena, Italy.
  • Santi D; Department of Biomedical, Metabolic and Neural Sciences, University of Modena & Reggio Emilia, Modena, Italy Azienda USL of Modena, Modena, Italy santi.daniele@gmail.com.
  • Negri L; Department of Gynecology, Division of Gynecology and Reproductive Medicine, Humanitas Fertility Center, Humanitas Research Hospital, Rozzano (Milan), Italy.
  • Hoffmann I; Center for Reproductive Medicine and Andrology, Martin Luther University Halle-Wittenberg, Halle, Germany.
  • Muratori M; Department of Experimental and Clinical Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Firenze, Italy.
  • Baldi E; Department of Experimental and Clinical Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Firenze, Italy.
  • Cambi M; Department of Experimental and Clinical Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Firenze, Italy.
  • Marcou M; Center for Reproductive Medicine and Andrology, Martin Luther University Halle-Wittenberg, Halle, Germany.
  • Greither T; Center for Reproductive Medicine and Andrology, Martin Luther University Halle-Wittenberg, Halle, Germany.
  • Baraldi E; Department of Laboratory Medicine and Pathological Anatomy, Azienda USL of Modena, Modena, Italy.
  • Tagliavini S; Department of Laboratory Medicine and Pathological Anatomy, Azienda USL of Modena, Modena, Italy.
  • Carra D; Department of Laboratory Medicine and Pathological Anatomy, Azienda USL of Modena, Modena, Italy.
  • Lombardo F; Department of Experimental Medicine, University of Rome "La Sapienza", Roma, Italy.
  • Gandini L; Department of Experimental Medicine, University of Rome "La Sapienza", Roma, Italy.
  • Pallotti F; Department of Experimental Medicine, University of Rome "La Sapienza", Roma, Italy.
  • Krausz C; Department of Experimental and Clinical Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Firenze, Italy.
  • Rastrelli G; Department of Experimental and Clinical Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Firenze, Italy.
  • Ferlin A; Department of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Padova, Italy.
  • Menegazzo M; Department of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Padova, Italy.
  • Pignatti E; Department of Biomedical, Metabolic and Neural Sciences, University of Modena & Reggio Emilia, Modena, Italy Center for Genomic Research, University of Modena & Reggio Emilia, Modena, Italy.
  • Linari F; Department of Biomedical, Metabolic and Neural Sciences, University of Modena & Reggio Emilia, Modena, Italy Azienda USL of Modena, Modena, Italy.
  • Marino M; Department of Biomedical, Metabolic and Neural Sciences, University of Modena & Reggio Emilia, Modena, Italy Center for Genomic Research, University of Modena & Reggio Emilia, Modena, Italy.
  • Benaglia R; Department of Gynecology, Division of Gynecology and Reproductive Medicine, Humanitas Fertility Center, Humanitas Research Hospital, Rozzano (Milan), Italy.
  • Levi-Setti PE; Department of Gynecology, Division of Gynecology and Reproductive Medicine, Humanitas Fertility Center, Humanitas Research Hospital, Rozzano (Milan), Italy.
  • Behre HM; Center for Reproductive Medicine and Andrology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Hum Reprod ; 31(9): 1960-9, 2016 09.
Article in En | MEDLINE | ID: mdl-27329968
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, FSH / Polymorphism, Single Nucleotide / Follicle Stimulating Hormone, Human / DNA Fragmentation / Infertility, Male Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans / Male Language: En Journal: Hum Reprod Journal subject: MEDICINA REPRODUTIVA Year: 2016 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, FSH / Polymorphism, Single Nucleotide / Follicle Stimulating Hormone, Human / DNA Fragmentation / Infertility, Male Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans / Male Language: En Journal: Hum Reprod Journal subject: MEDICINA REPRODUTIVA Year: 2016 Document type: Article Affiliation country: Country of publication: