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Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation.
Garg, Aditya; Zhao, Angela; Erickson, Sarah L; Mukherjee, Subhajit; Lau, Aik Jiang; Alston, Laurie; Chang, Thomas K H; Mani, Sridhar; Hirota, Simon A.
Affiliation
  • Garg A; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Zhao A; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Erickson SL; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Mukherjee S; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Lau AJ; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Alston L; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Chang TK; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Mani S; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
  • Hirota SA; Department of Physiology and Pharmacology (A.G., A.Z., S.L.E., L.A., S.A.H.), and Department of Microbiology, Immunology and Infectious Diseases (S.A.H.), University of Calgary, Calgary, Alberta, Canada; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Su.M., Sr.M.); and
J Pharmacol Exp Ther ; 359(1): 91-101, 2016 10.
Article in En | MEDLINE | ID: mdl-27440420
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myosin-Light-Chain Kinase / Receptors, Steroid / Gene Expression Regulation, Enzymologic / Cytokines / Mitogen-Activated Protein Kinase 8 / Mitogen-Activated Protein Kinase 9 / Intestinal Mucosa Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Pharmacol Exp Ther Year: 2016 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myosin-Light-Chain Kinase / Receptors, Steroid / Gene Expression Regulation, Enzymologic / Cytokines / Mitogen-Activated Protein Kinase 8 / Mitogen-Activated Protein Kinase 9 / Intestinal Mucosa Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Pharmacol Exp Ther Year: 2016 Document type: Article Country of publication: