[Risk factors and prevention of postoperative pancreatitis after pancreatectomy]. / Faktory riska i profilaktika posleoperatsionnogo pankreatita pri rezektsionnykh vmeshatel'stvakh na podzheludochnoi zheleze.
Khirurgiia (Mosk)
; (7): 4-10, 2016.
Article
in Ru
| MEDLINE
| ID: mdl-27459481
ABSTRACT
AIM:
to improve the results of pancreatic resections through decrease of postoperative pancreatitis incidence. MATERIAL ANDMETHODS:
It was analyzed 207 patients who underwent pancreatic surgery for pancreatic tumor (n=137) or chronic pancreatitis (n=70). 22 risk factors of postoperative pancreatitis were analyzed in 112 patients retrospectively. In prospective study of 95 patients the efficacy of lornoxicam to prevent postoperative pancreatitis was assessed. 68 parameters of immune state were studied to estimate effect of lornoxicam.RESULTS:
Significant factors were mellow pancreatic parenchyma, tumoral disease, pancreatic duct diameter over 3 mm, pancreatric duct index over 0.2, body mass index over 27 kg/m2. Likelihood of postoperative pancreatitis was 40%, 63%, 74.3% and 88.9% if 2, 3, 4 and 5 factors were combined respectively. Preventive use of lornoxicam reduced significantly incidence of postoperative pancreatitis (p=0.042). Incidence of pancreatic fistula and arrosive bleeding was decreased insignificantly due to small number of observations.CONCLUSION:
Assessment of significant risk factors and use of medical prevention are available to decrease likelihood of postoperative pancreatitis.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pancreatectomy
/
Pancreatic Neoplasms
/
Pancreatitis
/
Postoperative Complications
/
Piroxicam
/
Pancreatitis, Chronic
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Ru
Journal:
Khirurgiia (Mosk)
Year:
2016
Document type:
Article
Affiliation country: