Detection and quantification of acidic drug residues in South African surface water using gas chromatography-mass spectrometry.
Chemosphere
; 168: 1042-1050, 2017 Feb.
Article
in En
| MEDLINE
| ID: mdl-27814951
ABSTRACT
A method was optimized for derivatization, separation, detection and quantification of salicylic acid, acetylsalicylic acid, nalidixic acid, ibuprofen, phenacetin, naproxen, ketoprofen, meclofenamic acid and diclofenac in surface water using gas chromatography-mass spectrometry. For most of the acidic drugs, recovery was in the range 60-110% and the percent standard deviation was below 15% for the entire method, with limits of detection ranging from 0.041 to 1.614 µg L-1. The developed method was applied in the analysis of acidic drugs in Umgeni River system, KwaZulu-Natal South Africa. All of the selected acidic drugs were detected and quantified, their concentration in Umgeni River system ranged from 0.0200 to 68.14 µg L-1.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Water Pollutants, Chemical
Type of study:
Diagnostic_studies
Country/Region as subject:
Africa
Language:
En
Journal:
Chemosphere
Year:
2017
Document type:
Article
Affiliation country: