[Effect of diglycylhistidine on the oxidation of ascorbate catalyzed by Cu(II)].
Yao Xue Xue Bao
; 24(2): 155-8, 1989.
Article
in Zh
| MEDLINE
| ID: mdl-2801140
ABSTRACT
Glycylglycylhistidine (GGH) was synthesized using mixed anhydride method, and Cu(II) GGH = 11 complex was identified using UV, ESR, CD, ORD and FAB/MS technique. The oxidation of ascorbate catalyzed by cupric ion in RPMI 1640 medium (pH 7.40) was studied. The activation energy E = 39.2 kJ/mol. The addition of GGH inhibited the oxidation of ascorbate catalyzed by cupric ion. The investigations with ESR and fluorimetry indicate that there are Cu(I), ascorbate radical (AH), O2-., H2O2 and .OH during the oxidation.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Oligopeptides
/
Ascorbic Acid
Limits:
Animals
Language:
Zh
Journal:
Yao Xue Xue Bao
Year:
1989
Document type:
Article