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Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
Mulcahy Levy, Jean M; Zahedi, Shadi; Griesinger, Andrea M; Morin, Andrew; Davies, Kurtis D; Aisner, Dara L; Kleinschmidt-DeMasters, B K; Fitzwalter, Brent E; Goodall, Megan L; Thorburn, Jacqueline; Amani, Vladimir; Donson, Andrew M; Birks, Diane K; Mirsky, David M; Hankinson, Todd C; Handler, Michael H; Green, Adam L; Vibhakar, Rajeev; Foreman, Nicholas K; Thorburn, Andrew.
Affiliation
  • Mulcahy Levy JM; Department of Pediatrics, University of Colorado Denver, Aurora, United States.
  • Zahedi S; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, United States.
  • Griesinger AM; Department of Pediatrics, University of Colorado Denver, Aurora, United States.
  • Morin A; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, United States.
  • Davies KD; Department of Pediatrics, University of Colorado Denver, Aurora, United States.
  • Aisner DL; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, United States.
  • Kleinschmidt-DeMasters BK; Department of Pediatrics, University of Colorado Denver, Aurora, United States.
  • Fitzwalter BE; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, United States.
  • Goodall ML; Department of Pathology, University of Colorado Denver, Aurora, United States.
  • Thorburn J; Department of Pathology, University of Colorado Denver, Aurora, United States.
  • Amani V; Department of Pathology, University of Colorado Denver, Aurora, United States.
  • Donson AM; Department of Neurosurgery, University of Colorado Denver, Aurora, United States.
  • Birks DK; Department of Pharmacology, University of Colorado Denver, Aurora, United States.
  • Mirsky DM; Department of Pharmacology, University of Colorado Denver, Aurora, United States.
  • Hankinson TC; Department of Pharmacology, University of Colorado Denver, Aurora, United States.
  • Handler MH; Department of Pediatrics, University of Colorado Denver, Aurora, United States.
  • Green AL; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, United States.
  • Vibhakar R; Department of Pediatrics, University of Colorado Denver, Aurora, United States.
  • Foreman NK; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, United States.
  • Thorburn A; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, United States.
Elife ; 62017 01 17.
Article in En | MEDLINE | ID: mdl-28094001
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Sulfonamides / Brain Neoplasms / Chloroquine / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Indoles / Antineoplastic Agents Limits: Humans Language: En Journal: Elife Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Sulfonamides / Brain Neoplasms / Chloroquine / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Indoles / Antineoplastic Agents Limits: Humans Language: En Journal: Elife Year: 2017 Document type: Article Affiliation country: Country of publication: