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Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.
Hellerud, Bernt C; Orrem, Hilde L; Dybwik, Knut; Pischke, Søren E; Baratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grethe; Christiansen, Dorte; Nunn, Miles A; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik W; Mollnes, Tom E.
Affiliation
  • Hellerud BC; Department of Immunology, Oslo University Hospital Rikshospitalet, and K.G. Jebsen IRC, University of Oslo, N-0027 Oslo, Norway.
  • Orrem HL; Department of Pediatrics, Oslo University Hospital Ullevål and University of Oslo, Oslo, Norway.
  • Dybwik K; Department of Immunology, Oslo University Hospital Rikshospitalet, and K.G. Jebsen IRC, University of Oslo, N-0027 Oslo, Norway.
  • Pischke SE; Department of Anesthesiology, Nordland Hospital and Nord University, Bodø, Norway.
  • Baratt-Due A; Department of Immunology, Oslo University Hospital Rikshospitalet, and K.G. Jebsen IRC, University of Oslo, N-0027 Oslo, Norway.
  • Castellheim A; Department of Immunology, Oslo University Hospital Rikshospitalet, and K.G. Jebsen IRC, University of Oslo, N-0027 Oslo, Norway.
  • Fure H; Department of Anesthesiology and Intensive Care Unit, Institution of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Bergseth G; Research Laboratory, Nordland Hospital, Bodø, Norway.
  • Christiansen D; Research Laboratory, Nordland Hospital, Bodø, Norway.
  • Nunn MA; Research Laboratory, Nordland Hospital, Bodø, Norway.
  • Espevik T; Akari Therapeutics Plc, London, UK.
  • Lau C; Centre of Molecular Inflammation Research and Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Brandtzæg P; Research Laboratory, Nordland Hospital, Bodø, Norway.
  • Nielsen EW; Department of Pediatrics, Oslo University Hospital Ullevål and University of Oslo, Oslo, Norway.
  • Mollnes TE; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
J Intensive Care ; 5: 21, 2017.
Article in En | MEDLINE | ID: mdl-28261486
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Prognostic_studies Language: En Journal: J Intensive Care Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Prognostic_studies Language: En Journal: J Intensive Care Year: 2017 Document type: Article Affiliation country: Country of publication: