Your browser doesn't support javascript.
loading
Efficient conversion of alkenes to chlorohydrins by a Ru-based artificial enzyme.
Lopez, Sarah; Rondot, Laurianne; Cavazza, Christine; Iannello, Marina; Boeri-Erba, Elisabetta; Burzlaff, Nicolai; Strinitz, Frank; Jorge-Robin, Adeline; Marchi-Delapierre, Caroline; Ménage, Stéphane.
Affiliation
  • Lopez S; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, Laboratoire de Chimie et Biologie des Métaux, BioCat, UMR 5249, France and CEA-Grenoble, DRF/BIG/CBM, F-Grenoble, France. stephane.menage@cea.fr.
  • Rondot L; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, Laboratoire de Chimie et Biologie des Métaux, BioCat, UMR 5249, France and CEA-Grenoble, DRF/BIG/CBM, F-Grenoble, France. stephane.menage@cea.fr.
  • Cavazza C; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, Laboratoire de Chimie et Biologie des Métaux, BioCat, UMR 5249, France and CEA-Grenoble, DRF/BIG/CBM, F-Grenoble, France. stephane.menage@cea.fr.
  • Iannello M; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, Laboratoire de Chimie et Biologie des Métaux, BioCat, UMR 5249, France and CEA-Grenoble, DRF/BIG/CBM, F-Grenoble, France. stephane.menage@cea.fr.
  • Boeri-Erba E; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, UMR CEA, IBS, F-38044 Grenoble, France.
  • Burzlaff N; Inorganic Chemistry, Department of Chemistry and Pharmacy & Interdisciplinary Center for Molecular Materials (ICMM), University of Erlangen-Nuremberg, Egerlandstraße 1, 91058 Erlangen, Germany.
  • Strinitz F; Inorganic Chemistry, Department of Chemistry and Pharmacy & Interdisciplinary Center for Molecular Materials (ICMM), University of Erlangen-Nuremberg, Egerlandstraße 1, 91058 Erlangen, Germany.
  • Jorge-Robin A; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, Laboratoire de Chimie et Biologie des Métaux, BioCat, UMR 5249, France and CEA-Grenoble, DRF/BIG/CBM, F-Grenoble, France. stephane.menage@cea.fr.
  • Marchi-Delapierre C; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, Laboratoire de Chimie et Biologie des Métaux, BioCat, UMR 5249, France and CEA-Grenoble, DRF/BIG/CBM, F-Grenoble, France. stephane.menage@cea.fr.
  • Ménage S; Université Grenoble Alpes, Laboratoire de Chimie et Biologie des Métaux, BioCE, F-Grenoble, France and CNRS, Laboratoire de Chimie et Biologie des Métaux, BioCat, UMR 5249, France and CEA-Grenoble, DRF/BIG/CBM, F-Grenoble, France. stephane.menage@cea.fr.
Chem Commun (Camb) ; 53(25): 3579-3582, 2017 Mar 23.
Article in En | MEDLINE | ID: mdl-28289745
ABSTRACT
Artificial enzymes are required to catalyse non-natural reactions. Here, a hybrid catalyst was developed by embedding a novel Ru complex in the transport protein NikA. The protein scaffold activates the bound Ru complex to produce a catalyst with high regio- and stereo-selectivity. The hybrid efficiently and stably produced α-hydroxy-ß-chloro chlorohydrins from alkenes (up to 180 TON with a TOF of 1050 h-1).
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ruthenium / Chlorohydrins / Alkenes Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2017 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ruthenium / Chlorohydrins / Alkenes Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2017 Document type: Article Affiliation country: