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Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes.
Nezu, Masahiro; Souma, Tomokazu; Yu, Lei; Sekine, Hiroki; Takahashi, Nobuyuki; Wei, Andrew Zu-Sern; Ito, Sadayoshi; Fukamizu, Akiyoshi; Zsengeller, Zsuzsanna K; Nakamura, Tomohiro; Hozawa, Atsushi; Karumanchi, S Ananth; Suzuki, Norio; Yamamoto, Masayuki.
Affiliation
  • Nezu M; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Souma T; Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Yu L; Division of Oxygen Biology, United Centers for Advanced Research and Translational Medicine, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Sekine H; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Takahashi N; Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Wei AZ; Division of Nephrology-Hypertension, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Ito S; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Fukamizu A; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Zsengeller ZK; Division of Oxygen Biology, United Centers for Advanced Research and Translational Medicine, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Nakamura T; Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Hozawa A; Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai 9808578, Japan.
  • Karumanchi SA; Division of Nephrology-Hypertension, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Suzuki N; Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan.
  • Yamamoto M; Life Science Center of Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 3058577, Japan.
Sci Signal ; 10(479)2017 May 16.
Article in En | MEDLINE | ID: mdl-28512147
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placenta / Pre-Eclampsia / Reactive Oxygen Species / Neovascularization, Physiologic / NF-E2-Related Factor 2 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2017 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placenta / Pre-Eclampsia / Reactive Oxygen Species / Neovascularization, Physiologic / NF-E2-Related Factor 2 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2017 Document type: Article Affiliation country: