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Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.
Dalvi, Maithili P; Wang, Lei; Zhong, Rui; Kollipara, Rahul K; Park, Hyunsil; Bayo, Juan; Yenerall, Paul; Zhou, Yunyun; Timmons, Brenda C; Rodriguez-Canales, Jaime; Behrens, Carmen; Mino, Barbara; Villalobos, Pamela; Parra, Edwin R; Suraokar, Milind; Pataer, Apar; Swisher, Stephen G; Kalhor, Neda; Bhanu, Natarajan V; Garcia, Benjamin A; Heymach, John V; Coombes, Kevin; Xie, Yang; Girard, Luc; Gazdar, Adi F; Kittler, Ralf; Wistuba, Ignacio I; Minna, John D; Martinez, Elisabeth D.
Affiliation
  • Dalvi MP; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Wang L; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Zhong R; Department of Clinical Science, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Kollipara RK; Eugene McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Park H; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Bayo J; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Yenerall P; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Eugene McDermott Center for Human Growth and Development, The U
  • Zhou Y; Department of Clinical Science, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Timmons BC; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Rodriguez-Canales J; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Behrens C; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Mino B; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Villalobos P; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Parra ER; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Suraokar M; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Pataer A; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Swisher SG; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Kalhor N; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Bhanu NV; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Garcia BA; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Heymach JV; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Coombes K; Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
  • Xie Y; Department of Clinical Science, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Girard L; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Gazdar AF; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Kittler R; Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Eugene McDermott Center for Human Growth and Development, The University of Texas S
  • Wistuba II; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Minna JD; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwester
  • Martinez ED; Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwester
Cell Rep ; 19(8): 1669-1684, 2017 05 23.
Article in En | MEDLINE | ID: mdl-28538184
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged-Ring Compounds / Carboplatin / Carcinoma, Non-Small-Cell Lung / Drug Resistance, Neoplasm / Taxoids / Enzyme Inhibitors / Jumonji Domain-Containing Histone Demethylases / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Cell Rep Year: 2017 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged-Ring Compounds / Carboplatin / Carcinoma, Non-Small-Cell Lung / Drug Resistance, Neoplasm / Taxoids / Enzyme Inhibitors / Jumonji Domain-Containing Histone Demethylases / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Cell Rep Year: 2017 Document type: Article Affiliation country: Country of publication: