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Manual morphometry of hippocampus and amygdala in adults with attention-deficit hyperactivity disorder.
Nickel, Kathrin; Tebartz van Elst, Ludger; Perlov, Evgeniy; Jitten-Schachenmeier, Renate; Beier, Daniel; Endres, Dominique; Goll, Peter; Philipsen, Alexandra; Maier, Simon.
Affiliation
  • Nickel K; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany. Electronic address: kathrin.nickel@uniklinik-freiburg.de.
  • Tebartz van Elst L; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany.
  • Perlov E; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany; Luzerner Psychiatrie, Hospital St. Urban, Schafmattstrasse 1, 4915 St. Urban, Switzerland.
  • Jitten-Schachenmeier R; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany.
  • Beier D; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany.
  • Endres D; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany.
  • Goll P; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany.
  • Philipsen A; Medical Campus University of Oldenburg, School of Medicine and Health Sciences, Psychiatry and Psychotherapy - University Hospital Karl-Jaspers-Hospital, Hermann-Ehlers-Str. 7, 26160 Bad Zwischenahn, Germany.
  • Maier S; Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany.
Psychiatry Res Neuroimaging ; 267: 32-35, 2017 Sep 30.
Article in En | MEDLINE | ID: mdl-28734177
Previous studies have pointed to the involvement of limbic structures in the genesis of attention deficit hyperactivity disorder (ADHD). The present researchers manually segmented magnetic resonance images of 30 individuals with ADHD and 30 individually matched controls, focusing on amygdala and hippocampus volumes. Neither hippocampus nor amygdala volume differed significantly between individuals with and without ADHD. However, ADHD patients with higher hyperactivity scores had significantly smaller left amygdala volumes. This finding suggests that limbic alterations are significant in hyperactive symptoms in the pathophysiology of ADHD.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Attention Deficit Disorder with Hyperactivity / Hippocampus / Amygdala Type of study: Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Psychiatry Res Neuroimaging Year: 2017 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Attention Deficit Disorder with Hyperactivity / Hippocampus / Amygdala Type of study: Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Psychiatry Res Neuroimaging Year: 2017 Document type: Article Country of publication: