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Atorvastatin increases Fads1, Fads2 and Elovl5 gene expression via the geranylgeranyl pyrophosphate-dependent Rho kinase pathway in 3T3-L1 cells.
Ishihara, Noriko; Suzuki, Sawako; Tanaka, Shou; Watanabe, Yasuhiro; Nagayama, Daiji; Saiki, Atsuhito; Tanaka, Tomoaki; Tatsuno, Ichiro.
Affiliation
  • Ishihara N; Center for Diabetes, Metabolism and Endocrinology, Toho University Sakura Medical Center, Sakura, Chiba 285­8741, Japan.
  • Suzuki S; Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Chiba 260­8670, Japan.
  • Tanaka S; Center for Diabetes, Metabolism and Endocrinology, Toho University Sakura Medical Center, Sakura, Chiba 285­8741, Japan.
  • Watanabe Y; Center for Diabetes, Metabolism and Endocrinology, Toho University Sakura Medical Center, Sakura, Chiba 285­8741, Japan.
  • Nagayama D; Center for Diabetes, Metabolism and Endocrinology, Toho University Sakura Medical Center, Sakura, Chiba 285­8741, Japan.
  • Saiki A; Center for Diabetes, Metabolism and Endocrinology, Toho University Sakura Medical Center, Sakura, Chiba 285­8741, Japan.
  • Tanaka T; Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, Chiba, Chiba 260­8670, Japan.
  • Tatsuno I; Center for Diabetes, Metabolism and Endocrinology, Toho University Sakura Medical Center, Sakura, Chiba 285­8741, Japan.
Mol Med Rep ; 16(4): 4756-4762, 2017 Oct.
Article in En | MEDLINE | ID: mdl-28765914
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyisoprenyl Phosphates / Acetyltransferases / Gene Expression Regulation, Enzymologic / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Rho-Associated Kinases / Fatty Acid Desaturases / Atorvastatin Limits: Animals Language: En Journal: Mol Med Rep Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyisoprenyl Phosphates / Acetyltransferases / Gene Expression Regulation, Enzymologic / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Rho-Associated Kinases / Fatty Acid Desaturases / Atorvastatin Limits: Animals Language: En Journal: Mol Med Rep Year: 2017 Document type: Article Affiliation country: Country of publication: