ELMSTREET (Esophageal Lesions during MitraClip uSing TRansEsophageal Echocardiography Trial).
EuroIntervention
; 13(12): e1444-e1451, 2017 12 08.
Article
in En
| MEDLINE
| ID: mdl-28804054
ABSTRACT
AIMS:
We aimed to evaluate possible detrimental effects of transoesophageal echocardiography (TEE) on the oesophageal tissue during percutaneous mitral valve repair (PMVR). METHODS ANDRESULTS:
From March 2014 to July 2015, 186 patients were treated for severe mitral regurgitation with PMVR using the MitraClip system. In 40 patients, oesophago-gastro-duodenoscopy was performed due to symptoms related to the gastrointestinal tract. Based on the procedure duration, patients were classified into group 1 (>60 minutes, n=23) or into group 2 (<60 minutes, n=17), respectively. Oesophageal lesions (OL) were found in 19 patients (group 1 n=17 vs. group 2 n=2, p<0.0001). We observed a change in leucocyte count after the procedure (group 1 +2.00 Gpt/L [SEM±0.48] vs. group 2 +0.54 Gpt/L [SEM±0.36], p=0.028). This change was more apparent when comparing patients with OL vs. those without (lesions +2.65 Gpt/L [SEM±0.56] vs. no lesions +0.23 Gpt/L [SEM±0.12], p<0.0001).CONCLUSIONS:
Prolonged use of TEE during PMVR with a procedure time of longer than 60 minutes increases the risk of oesophageal damage. An exceptional rise of leucocyte count after PMVR may raise suspicion of new oesophageal damage.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Registries
/
Echocardiography, Transesophageal
/
Esophagus
/
Endovascular Procedures
/
Mitral Valve Insufficiency
Type of study:
Observational_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
En
Journal:
EuroIntervention
Journal subject:
ANGIOLOGIA
/
CARDIOLOGIA
/
TERAPEUTICA
Year:
2017
Document type:
Article
Affiliation country: