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Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.
Liu, Renhe; Lyu, Xiaoxuan; Batt, Sarah M; Hsu, Mei-Hui; Harbut, Michael B; Vilchèze, Catherine; Cheng, Bo; Ajayi, Kehinde; Yang, Baiyuan; Yang, Yun; Guo, Hui; Lin, Changyou; Gan, Fei; Wang, Chen; Franzblau, Scott G; Jacobs, William R; Besra, Gurdyal S; Johnson, Eric F; Petrassi, Mike; Chatterjee, Arnab K; Fütterer, Klaus; Wang, Feng.
Affiliation
  • Liu R; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Lyu X; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Batt SM; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Hsu MH; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA.
  • Harbut MB; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Vilchèze C; Howard Hughes Medical Institute, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, UK.
  • Cheng B; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Ajayi K; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Yang B; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Yang Y; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Guo H; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Lin C; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Gan F; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Wang C; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois, Chicago, IL, 60612, USA.
  • Jacobs WR; Howard Hughes Medical Institute, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, UK.
  • Besra GS; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Johnson EF; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA.
  • Petrassi M; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Chatterjee AK; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
  • Fütterer K; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Wang F; California Institute for Biomedical Research (Calibr), La Jolla, CA, 92037, USA.
Angew Chem Int Ed Engl ; 56(42): 13011-13015, 2017 10 09.
Article in En | MEDLINE | ID: mdl-28815830
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiophenes / Bacterial Proteins / Cytochrome P-450 CYP2C9 / Mycobacterium tuberculosis / Antitubercular Agents Limits: Animals Language: En Journal: Angew Chem Int Ed Engl Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiophenes / Bacterial Proteins / Cytochrome P-450 CYP2C9 / Mycobacterium tuberculosis / Antitubercular Agents Limits: Animals Language: En Journal: Angew Chem Int Ed Engl Year: 2017 Document type: Article Affiliation country: Country of publication: