Review of current typhoid fever vaccines, cross-protection against paratyphoid fever, and the European guidelines.
Expert Rev Vaccines
; 16(10): 1029-1043, 2017 10.
Article
in En
| MEDLINE
| ID: mdl-28856924
ABSTRACT
INTRODUCTION:
Typhoid and paratyphoid fever remain a global health problem, which - in non-endemic countries - are mainly seen in travelers, particularly in VFRs (visiting friends and relatives), with occasional local outbreaks occurring. A rise in anti-microbial resistance emphasizes the role of preventive measures, especially vaccinations against typhoid and paratyphoid fever for travelers visiting endemic countries. Areas covered This state-of-the-art review recapitulates the epidemiology and mechanisms of disease of typhoid and paratyphoid fever, depicts the perspective of non-endemic countries and travelers (VFRs), and collectively presents current European recommendations for typhoid fever vaccination. We provide a brief overview of available (and developmental) vaccines in Europe, present current data on cross-protection to S. Paratyphi, and aim to provide a background for typhoid vaccine decision-making in travelers. Expert commentary European recommendations are not harmonized. Experts must assess vaccination of travelers based on current country-specific recommendations. Travel health practitioners should be aware of the issues surrounding vaccination of travelers and be motivated to increase awareness of typhoid and paratyphoid fever risks.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Typhoid Fever
/
Typhoid-Paratyphoid Vaccines
/
Vaccination
/
Paratyphoid Fever
/
Cross Protection
Type of study:
Guideline
/
Prognostic_studies
Limits:
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Expert Rev Vaccines
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2017
Document type:
Article
Affiliation country: