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WIPI ß-propellers function as scaffolds for STK11/LKB1-AMPK and AMPK-related kinase signaling in autophagy.
Bakula, Daniela; Mueller, Amelie J; Proikas-Cezanne, Tassula.
Affiliation
  • Bakula D; a Department of Molecular Biology, Interfaculty Institute of Cell Biology , Eberhard Karls University Tuebingen , Germany.
  • Mueller AJ; b International Max Planck Research School 'From Molecules to Organisms' , Max Planck Institute for Developmental Biology and Eberhard Karls University Tuebingen , Germany.
  • Proikas-Cezanne T; a Department of Molecular Biology, Interfaculty Institute of Cell Biology , Eberhard Karls University Tuebingen , Germany.
Autophagy ; 14(6): 1082-1083, 2018.
Article in En | MEDLINE | ID: mdl-28976799
The article discusses new findings on the role of the 4 human WIPI proteins at the onset of macroautophagy/autophagy. New insights revealing a circuit scaffold function of WIPI ß-propellers that interconnect autophagy signaling control with appropriate autophagosome formation are summarized.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Signal Transduction / Protein Serine-Threonine Kinases / AMP-Activated Protein Kinases / Autophagy-Related Protein-1 Homolog Type of study: Prognostic_studies Limits: Humans Language: En Journal: Autophagy Year: 2018 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Signal Transduction / Protein Serine-Threonine Kinases / AMP-Activated Protein Kinases / Autophagy-Related Protein-1 Homolog Type of study: Prognostic_studies Limits: Humans Language: En Journal: Autophagy Year: 2018 Document type: Article Affiliation country: Country of publication: