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MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.
Lemaçon, Delphine; Jackson, Jessica; Quinet, Annabel; Brickner, Joshua R; Li, Shan; Yazinski, Stephanie; You, Zhongsheng; Ira, Grzegorz; Zou, Lee; Mosammaparast, Nima; Vindigni, Alessandro.
Affiliation
  • Lemaçon D; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA.
  • Jackson J; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA.
  • Quinet A; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA.
  • Brickner JR; Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA.
  • Li S; Department of Cell Biology and Physiology, Washington University School of Medicine, Campus Box 8228, 660S. Euclid Ave., St Louis, MO, 63110, USA.
  • Yazinski S; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
  • You Z; Department of Cell Biology and Physiology, Washington University School of Medicine, Campus Box 8228, 660S. Euclid Ave., St Louis, MO, 63110, USA.
  • Ira G; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  • Zou L; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
  • Mosammaparast N; Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA.
  • Vindigni A; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA. avindign@slu.edu.
Nat Commun ; 8(1): 860, 2017 10 16.
Article in En | MEDLINE | ID: mdl-29038425
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Carrier Proteins / BRCA2 Protein / DNA Repair Enzymes / DNA-Binding Proteins / DNA Polymerase III / Endonucleases / Exodeoxyribonucleases / MRE11 Homologue Protein Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Carrier Proteins / BRCA2 Protein / DNA Repair Enzymes / DNA-Binding Proteins / DNA Polymerase III / Endonucleases / Exodeoxyribonucleases / MRE11 Homologue Protein Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: Country of publication: