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MODOMICS: a database of RNA modification pathways. 2017 update.
Boccaletto, Pietro; Machnicka, Magdalena A; Purta, Elzbieta; Piatkowski, Pawel; Baginski, Blazej; Wirecki, Tomasz K; de Crécy-Lagard, Valérie; Ross, Robert; Limbach, Patrick A; Kotter, Annika; Helm, Mark; Bujnicki, Janusz M.
Affiliation
  • Boccaletto P; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, PL-02-109 Warsaw, Poland.
  • Machnicka MA; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, PL-02-109 Warsaw, Poland.
  • Purta E; Institute of Informatics, University of Warsaw, Banacha 2, PL-02-097 Warsaw, Poland.
  • Piatkowski P; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, PL-02-109 Warsaw, Poland.
  • Baginski B; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, PL-02-109 Warsaw, Poland.
  • Wirecki TK; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, PL-02-109 Warsaw, Poland.
  • de Crécy-Lagard V; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, PL-02-109 Warsaw, Poland.
  • Ross R; Microbiology and Cell Science Department, University of Florida, Gainesville, FL 32611, USA.
  • Limbach PA; Department of Chemistry, Rieveschl Laboratories for Mass Spectrometry, University of Cincinnati, Cincinnati, OH 45221, USA.
  • Kotter A; Department of Chemistry, Rieveschl Laboratories for Mass Spectrometry, University of Cincinnati, Cincinnati, OH 45221, USA.
  • Helm M; Institut für Pharmazie und Biochemie, Johannes Gutenberg-Universität, Staudinger Weg 5, D-55128 Mainz, Germany.
  • Bujnicki JM; Institut für Pharmazie und Biochemie, Johannes Gutenberg-Universität, Staudinger Weg 5, D-55128 Mainz, Germany.
Nucleic Acids Res ; 46(D1): D303-D307, 2018 01 04.
Article in En | MEDLINE | ID: mdl-29106616
MODOMICS is a database of RNA modifications that provides comprehensive information concerning the chemical structures of modified ribonucleosides, their biosynthetic pathways, the location of modified residues in RNA sequences, and RNA-modifying enzymes. In the current database version, we included the following new features and data: extended mass spectrometry and liquid chromatography data for modified nucleosides; links between human tRNA sequences and MINTbase - a framework for the interactive exploration of mitochondrial and nuclear tRNA fragments; new, machine-friendly system of unified abbreviations for modified nucleoside names; sets of modified tRNA sequences for two bacterial species, updated collection of mammalian tRNA modifications, 19 newly identified modified ribonucleosides and 66 functionally characterized proteins involved in RNA modification. Data from MODOMICS have been linked to the RNAcentral database of RNA sequences. MODOMICS is available at http://modomics.genesilico.pl.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleosides / RNA / Databases, Genetic Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2018 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleosides / RNA / Databases, Genetic Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2018 Document type: Article Affiliation country: Country of publication: