[Evolution of the Complexity Index of the antiretroviral therapy in HIV+ patients in a real life clinical practice]. / Evolución del índice de complejidad de la terapia antirretroviral en paciente VIH en una cohorte de práctica clínica real.
Rev Esp Quimioter
; 30(6): 429-435, 2017 Dec.
Article
in Es
| MEDLINE
| ID: mdl-29115368
ABSTRACT
OBJECTIVE:
HIV infection has been one of the biggest successes in the healthcare world, mainly due to the appearance of antiretroviral treatment (ART). The complexity of this type of treatment has been one of the decisive factors in the follow-up of these patients.METHODS:
An analytical, unicentric, retrospective observational study. We included all patients older than 18 years of age who were diagnosed with HIV who received ART in follow-up for the consultation of pharmaceutical pathology care during the year 2015. The evolution of the complexity index of ART over time and its relation with adherence to ART and concomitant treatment.RESULTS:
A total of 619 patients were included in the study with a mean age of 47.03 ± 10.18 years. There was a reduction in CI over the years, with a significant decrease in the year 2013 and in 2015. The results obtained after the analysis of the secondary variables showed a significant relation between the adhesion to the ART and the CI of this. Patients have a lower CI (3.5) than non-adherent patients (4.25). (P = 0.003).CONCLUSIONS:
The complexity of ART is being reduced mainly by new treatment strategies and the increasing appearance of pharmaceutical coformulations. A reduction in the complexity of ART assumes a better adherence to it.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
HIV Seropositivity
/
Antiretroviral Therapy, Highly Active
Type of study:
Observational_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Es
Journal:
Rev Esp Quimioter
Journal subject:
TERAPIA POR MEDICAMENTOS
Year:
2017
Document type:
Article