C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid.

Hornum, Lars; Hansen, Anker Jon; Tornehave, Ditte; Fjording, Marianne Scheel; Colmenero, Paula; Wätjen, Inger Falbe; Søe Nielsen, Niels Henrik; Bliddal, Henning; Bartels, Else Marie

Hornum, Lars; Hansen, Anker Jon; Tornehave, Ditte; Fjording, Marianne Scheel; Colmenero, Paula; Wätjen, Inger Falbe; Søe Nielsen, Niels Henrik; Bliddal, Henning; Bartels, Else Marie.

Affiliation

Hornum L; Novo Nordisk A/S, Måløv, Denmark.
Hansen AJ; Novo Nordisk A/S, Måløv, Denmark.
Tornehave D; Novo Nordisk A/S, Måløv, Denmark.
Fjording MS; Novo Nordisk A/S, Måløv, Denmark.
Colmenero P; Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Wätjen IF; The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Frederiksberg, Denmark.
Søe Nielsen NH; Hand Section, Department of Orthopaedics, Herlev and Gentofte Hospital, Gentofte, Denmark.
Bliddal H; The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Frederiksberg, Denmark.
Bartels EM; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

PLoS One ; 12(12): e0189017, 2017.

Article in En | MEDLINE | ID: mdl-29220376

Subject(s)

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Synovial Fluid / Arthritis, Psoriatic / Complement C5a / Chemotaxis, Leukocyte / Receptor, Anaphylatoxin C5a / Leukocytes Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Document type: Article Affiliation country: Country of publication:

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google