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The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers.
Moschetti, Viktoria; Kim, Maria; Sand, Michael; Wunderlich, Glen; Andersen, Grit; Feifel, Ulrich; Jang, In-Jin; Timmer, Wolfgang; Rosenbrock, Holger; Boland, Katja.
Affiliation
  • Moschetti V; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim am Rhein, Germany. Electronic address: viktoria.moschetti@boehringer-ingelheim.com.
  • Kim M; Boehringer Ingelheim Korea Ltd, Seoul, South Korea.
  • Sand M; Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, USA.
  • Wunderlich G; Boehringer Ingelheim (Canada) Ltd, Burlington, ON, Canada.
  • Andersen G; Profil Institut für Stoffwechselforschung GmbH, Neuss, Nordrhein Westfalen, Germany.
  • Feifel U; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim am Rhein, Germany.
  • Jang IJ; Seoul National University Hospital, Seoul, South Korea.
  • Timmer W; Inamed GmbH, Gauting, Germany.
  • Rosenbrock H; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
  • Boland K; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Eur Neuropsychopharmacol ; 28(5): 643-655, 2018 05.
Article in En | MEDLINE | ID: mdl-29567399
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Pyrazoles / Pyrimidines Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Eur Neuropsychopharmacol Journal subject: PSICOFARMACOLOGIA Year: 2018 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Pyrazoles / Pyrimidines Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Eur Neuropsychopharmacol Journal subject: PSICOFARMACOLOGIA Year: 2018 Document type: Article Country of publication: