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Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model.
Ishikawa, Kaori; Tanaka, Akira; Kogame, Akifumi; Watanabe, Tatsuya; Tagawa, Yoshihiko; Matsui, Hisanori.
Affiliation
  • Ishikawa K; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Tanaka A; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Kogame A; Drug Metabolism & Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Watanabe T; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Tagawa Y; Drug Metabolism & Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Matsui H; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan. Electronic address: hisanori.matsui@takeda.com.
Eur J Pharmacol ; 828: 126-134, 2018 Jun 05.
Article in En | MEDLINE | ID: mdl-29580912
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Xenograft Model Antitumor Assays / Kisspeptins / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2018 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Xenograft Model Antitumor Assays / Kisspeptins / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2018 Document type: Article Affiliation country: Country of publication: