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Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction.
Boland, Michelle L; Oldham, Stephanie; Boland, Brandon B; Will, Sarah; Lapointe, Jean-Martin; Guionaud, Silvia; Rhodes, Christopher J; Trevaskis, James L.
Affiliation
  • Boland ML; Cardiovascular and Metabolic Diseases, MedImmune LLC, Gaithersburg, MD 20878, United States.
  • Oldham S; Cardiovascular and Metabolic Diseases, MedImmune LLC, Gaithersburg, MD 20878, United States.
  • Boland BB; Cardiovascular and Metabolic Diseases, MedImmune LLC, Gaithersburg, MD 20878, United States.
  • Will S; Cardiovascular and Metabolic Diseases, MedImmune LLC, Gaithersburg, MD 20878, United States.
  • Lapointe JM; Pathology, MedImmune Ltd., Cambridge CB21 6GH, United Kingdom.
  • Guionaud S; Pathology, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge CB22 3AT, United Kingdom.
  • Rhodes CJ; Cardiovascular and Metabolic Diseases, MedImmune LLC, Gaithersburg, MD 20878, United States.
  • Trevaskis JL; Cardiovascular and Metabolic Diseases, MedImmune LLC, Gaithersburg, MD 20878, United States. trevaskisj@medimmune.com.
World J Gastroenterol ; 24(16): 1748-1765, 2018 Apr 28.
Article in En | MEDLINE | ID: mdl-29713129
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / Oxidative Stress / Non-alcoholic Fatty Liver Disease / Liver / Antioxidants Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: World J Gastroenterol Journal subject: GASTROENTEROLOGIA Year: 2018 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / Oxidative Stress / Non-alcoholic Fatty Liver Disease / Liver / Antioxidants Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: World J Gastroenterol Journal subject: GASTROENTEROLOGIA Year: 2018 Document type: Article Affiliation country: