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The cytotoxic effects of propolis on breast cancer cells involve PI3K/Akt and ERK1/2 pathways, mitochondrial membrane potential, and reactive oxygen species generation.
Frión-Herrera, Yahima; Díaz-García, Alexis; Ruiz-Fuentes, Jenny; Rodríguez-Sánchez, Hermis; Sforcin, José M.
Affiliation
  • Frión-Herrera Y; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil.
  • Díaz-García A; Laboratories of Biofarmaceuticals and Chemistries Productions (LABIOFAM), Havana, Cuba.
  • Ruiz-Fuentes J; Tropical Medicine Institute Pedro Kouri, Havana, Cuba.
  • Rodríguez-Sánchez H; Tropical Medicine Institute Pedro Kouri, Havana, Cuba.
  • Sforcin JM; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil. sforcin@ibb.unesp.br.
Inflammopharmacology ; 27(5): 1081-1089, 2019 Oct.
Article in En | MEDLINE | ID: mdl-29748880
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Breast Neoplasms / Reactive Oxygen Species / Phosphatidylinositol 3-Kinases / MAP Kinase Signaling System / Proto-Oncogene Proteins c-akt / Membrane Potential, Mitochondrial Limits: Female / Humans Language: En Journal: Inflammopharmacology Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2019 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Breast Neoplasms / Reactive Oxygen Species / Phosphatidylinositol 3-Kinases / MAP Kinase Signaling System / Proto-Oncogene Proteins c-akt / Membrane Potential, Mitochondrial Limits: Female / Humans Language: En Journal: Inflammopharmacology Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2019 Document type: Article Affiliation country: Country of publication: