[Response predictors for physical training HFrEF patients].
Kardiologiia
; (S4): 22-28, 2018.
Article
in Ru
| MEDLINE
| ID: mdl-29782279
ABSTRACT
PURPOSE:
To identify different types and possible predictors of physical rehabilitation (PR) response in reduced ejection fraction heart failure (HFrEF) patients, selected on the basis of achievement the lactate threshold during cardiopulmonary exercising test (CPET).METHODS:
64 patients, chronic heart failure (CHF) NYHA II-III functional class were included in our study. Mean age 54±12,5 years, body mass index (BMI) 26,5±6,4 kg/m2, ejection fraction (EF) 26,4±1,4 %, NYHA II III (67 % 33 % patients). The original estimated results of physical examination, laboratory parameters, CPET, quality of life (QOL), exercise tolerance (ET) and echocardiography (EchoCG). Physical rehabilitation (PR) efficiency was estimated on the basis of peak oxygen uptake (VO2peak), QOL and ET dynamics after 1,3 and 6 months; EF dynamics was estimated after 6 months. Data were statistically processed using software package "Statistika, 9.0".RESULTS:
After 6 months PR EF increased by 7,5±0,5 %, QOL - 17.5±8 points, ET - 9.5±1 points and VO2 peak - 4.4 ml/min/kg, end-diastolic volume decreased by 6±2.0 ml from baseline (p1,2,3,4, respectively). Echocardiography, CPET, QOL and ET improvement revealed a significant number of patients (EF - 48 %, VO2 peak - 64 %, QOL - 64 %, ET - 67 % of patients, respectively). Revealed a strong positive correlation between the initial values of VO2 peak and EF (rEF=0,4, p), and between baseline levels of sodium, haemoglobin and the of PR efficiency (rNa= 0,41, p,0,05; rHb = 0,45, p.Key words
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Quality of Life
/
Heart Failure
Type of study:
Prognostic_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Adult
/
Aged
/
Humans
/
Middle aged
Language:
Ru
Journal:
Kardiologiia
Year:
2018
Document type:
Article