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Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells.
Winge, Sofia Boeg; Dalgaard, Marlene Danner; Belling, Kirstine G; Jensen, Jacob Malte; Nielsen, John Erik; Aksglaede, Lise; Schierup, Mikkel Heide; Brunak, Søren; Skakkebæk, Niels Erik; Juul, Anders; Rajpert-De Meyts, Ewa; Almstrup, Kristian.
Affiliation
  • Winge SB; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Dalgaard MD; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Belling KG; DTU Multi-Assay Core, DTU Bioinformatics, Technical University of Denmark, Kongens Lyngby, Denmark.
  • Jensen JM; Translational Disease Systems Biology Group, Novo Nordisk Foundation for Protein Research, University of Copenhagen, Copenhagen, Denmark.
  • Nielsen JE; Bioinformatics Research Center, Aarhus University, Aarhus, Denmark.
  • Aksglaede L; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Schierup MH; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Brunak S; Bioinformatics Research Center, Aarhus University, Aarhus, Denmark.
  • Skakkebæk NE; Translational Disease Systems Biology Group, Novo Nordisk Foundation for Protein Research, University of Copenhagen, Copenhagen, Denmark.
  • Juul A; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Rajpert-De Meyts E; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Almstrup K; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Cell Death Dis ; 9(6): 586, 2018 05 22.
Article in En | MEDLINE | ID: mdl-29789566
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sertoli Cells / Testis / Cell Differentiation / Gene Expression Profiling / Klinefelter Syndrome / Leydig Cells Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Humans / Male Language: En Journal: Cell Death Dis Year: 2018 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sertoli Cells / Testis / Cell Differentiation / Gene Expression Profiling / Klinefelter Syndrome / Leydig Cells Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Humans / Male Language: En Journal: Cell Death Dis Year: 2018 Document type: Article Affiliation country: Country of publication: