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Highly Potent Clickable Probe for Cellular Imaging of MDM2 and Assessing Dynamic Responses to MDM2-p53 Inhibition.
Lebraud, Honorine; Noble, Richard A; Phillips, Nicole; Heam, Keisha; Castro, Juan; Zhao, Yan; Newell, David R; Lunec, John; Wedge, Stephen R; Heightman, Tom D.
Affiliation
  • Lebraud H; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
  • Noble RA; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Phillips N; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Heam K; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
  • Castro J; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
  • Zhao Y; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Newell DR; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Lunec J; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Wedge SR; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Heightman TD; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
Bioconjug Chem ; 29(6): 2100-2106, 2018 06 20.
Article in En | MEDLINE | ID: mdl-29851469
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Boron Compounds / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-mdm2 / Para-Aminobenzoates / Fluorescent Dyes Limits: Humans Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Boron Compounds / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-mdm2 / Para-Aminobenzoates / Fluorescent Dyes Limits: Humans Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Country of publication: