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A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor.
Wang, Jiawan; Yao, Zhan; Jonsson, Philip; Allen, Amy N; Qin, Alice Can Ran; Uddin, Sharmeen; Dunkel, Ira J; Petriccione, Mary; Manova, Katia; Haque, Sofia; Rosenblum, Marc K; Pisapia, David J; Rosen, Neal; Taylor, Barry S; Pratilas, Christine A.
Affiliation
  • Wang J; Division of Pediatric Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
  • Yao Z; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Jonsson P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Allen AN; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Qin ACR; Division of Pediatric Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
  • Uddin S; Division of Pediatric Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
  • Dunkel IJ; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Petriccione M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Manova K; Department of Pediatrics, Weill Cornell Medical College, New York, New York.
  • Haque S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Rosenblum MK; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Pisapia DJ; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Rosen N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Taylor BS; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York.
  • Pratilas CA; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Cancer Discov ; 8(9): 1130-1141, 2018 09.
Article in En | MEDLINE | ID: mdl-29880583

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Mutation Type of study: Risk_factors_studies Limits: Adolescent / Humans / Male Language: En Journal: Cancer Discov Year: 2018 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Mutation Type of study: Risk_factors_studies Limits: Adolescent / Humans / Male Language: En Journal: Cancer Discov Year: 2018 Document type: Article