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An inhibitor of oxidative phosphorylation exploits cancer vulnerability.
Molina, Jennifer R; Sun, Yuting; Protopopova, Marina; Gera, Sonal; Bandi, Madhavi; Bristow, Christopher; McAfoos, Timothy; Morlacchi, Pietro; Ackroyd, Jeffrey; Agip, Ahmed-Noor A; Al-Atrash, Gheath; Asara, John; Bardenhagen, Jennifer; Carrillo, Caroline C; Carroll, Christopher; Chang, Edward; Ciurea, Stefan; Cross, Jason B; Czako, Barbara; Deem, Angela; Daver, Naval; de Groot, John Frederick; Dong, Jian-Wen; Feng, Ningping; Gao, Guang; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Giuliani, Virginia; Han, Jing; Han, Lina; Henry, Verlene K; Hirst, Judy; Huang, Sha; Jiang, Yongying; Kang, Zhijun; Khor, Tin; Konoplev, Sergej; Lin, Yu-Hsi; Liu, Gang; Lodi, Alessia; Lofton, Timothy; Ma, Helen; Mahendra, Mikhila; Matre, Polina; Mullinax, Robert; Peoples, Michael; Petrocchi, Alessia; Rodriguez-Canale, Jaime; Serreli, Riccardo.
Affiliation
  • Molina JR; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Sun Y; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Protopopova M; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gera S; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bandi M; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bristow C; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • McAfoos T; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Morlacchi P; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ackroyd J; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Agip AA; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Al-Atrash G; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Asara J; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bardenhagen J; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Carrillo CC; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Carroll C; Agilent Technologies Inc., Lexington, MA, USA.
  • Chang E; Department of Cancer Imaging Systems, University of Texas MD Cancer Center, Houston, TX, USA.
  • Ciurea S; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge, UK.
  • Cross JB; Department of Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Czako B; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Deem A; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Daver N; Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • de Groot JF; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Dong JW; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Feng N; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gao G; Department of Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gay J; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Do MG; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Greer J; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Giuliani V; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Han J; Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Han L; Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Henry VK; Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Hirst J; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Huang S; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Jiang Y; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kang Z; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Khor T; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Konoplev S; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lin YH; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Liu G; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lodi A; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lofton T; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ma H; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Mahendra M; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Matre P; Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Mullinax R; Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Peoples M; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge, UK.
  • Petrocchi A; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Rodriguez-Canale J; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Serreli R; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nat Med ; 24(7): 1036-1046, 2018 07.
Article in En | MEDLINE | ID: mdl-29892070
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Phosphorylation / Neoplasms Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2018 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Phosphorylation / Neoplasms Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2018 Document type: Article Affiliation country: Country of publication: