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Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling.
Zhao, Xiang; Sankaran, Shvetha; Yap, Jiawei; Too, Chien Tei; Ho, Zi Zong; Dolton, Garry; Legut, Mateusz; Ren, Ee Chee; Sewell, Andrew K; Bertoletti, Antonio; MacAry, Paul A; Brzostek, Joanna; Gascoigne, Nicholas R J.
Affiliation
  • Zhao X; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore, 117545, Singapore.
  • Sankaran S; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore, 117545, Singapore.
  • Yap J; Immunology Programme, Life Sciences Institute, National University of Singapore, 28 Medical Drive, Centre for Life Sciences, Level 3, Singapore, 117456, Singapore.
  • Too CT; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore, 117545, Singapore.
  • Ho ZZ; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore, 117545, Singapore.
  • Dolton G; Immunology Programme, Life Sciences Institute, National University of Singapore, 28 Medical Drive, Centre for Life Sciences, Level 3, Singapore, 117456, Singapore.
  • Legut M; Emerging Infectious Diseases Program, Duke-NUS Graduate Medical School, 8 College Road, Singapore, 169857, Singapore.
  • Ren EC; Division of Infection and Immunity, Cardiff University School of Medicine, Henry Wellcome Building, University Hospital Wales, Heath Park, Cardiff, CF14 4XN, United Kingdom.
  • Sewell AK; Division of Infection and Immunity, Cardiff University School of Medicine, Henry Wellcome Building, University Hospital Wales, Heath Park, Cardiff, CF14 4XN, United Kingdom.
  • Bertoletti A; Singapore Immunology Network, A*STAR, 8A Biomedical Grove, Immunos #03-06, Singapore, 138648, Singapore.
  • MacAry PA; Division of Infection and Immunity, Cardiff University School of Medicine, Henry Wellcome Building, University Hospital Wales, Heath Park, Cardiff, CF14 4XN, United Kingdom.
  • Brzostek J; Systems Immunity Research Institute, Cardiff University, Tenovus Building, Cardiff, CF14 4XN, United Kingdom.
  • Gascoigne NRJ; Emerging Infectious Diseases Program, Duke-NUS Graduate Medical School, 8 College Road, Singapore, 169857, Singapore.
Nat Commun ; 9(1): 2716, 2018 07 13.
Article in En | MEDLINE | ID: mdl-30006605
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Receptors, Antigen, T-Cell / T-Lymphocytes, Cytotoxic / Signal Transduction / HLA-A2 Antigen / Epitopes / Antigens Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Receptors, Antigen, T-Cell / T-Lymphocytes, Cytotoxic / Signal Transduction / HLA-A2 Antigen / Epitopes / Antigens Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: Country of publication: