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Adult Henolch-Schonlein purpura: multiorgan failure in the setting of a purpuric rash.
Maxfield, Luke; Peck, Aurora; Youngblood, Laura Bond.
Affiliation
  • Maxfield L; Internal Medicine, University of Tennessee at Chattanooga, College of Health Education and Professional Studies, Chattanooga, Tennessee, USA.
  • Peck A; Dermatology, Sampson Regional Medical Center, Clinton, NC, USA.
  • Youngblood LB; College of Medicine, University of Tennessee at Chattanooga, College of Health Education and Professional Studies, Chattanooga, Tennessee, USA.
BMJ Case Rep ; 20182018 Aug 09.
Article in En | MEDLINE | ID: mdl-30093466
We report a 66-year-old man with a history of congestive heart failure, atrial fibrillation on warfarin therapy and chronic kidney disease that presented with acute dyspnoea. He had multiple palpable purpuric lesions on his bilateral lower extremities. Laboratory findings supported acute anaemia with no obvious bleeding source, supratherapeutic international normalised ratio and acute on chronic kidney injury. Oesophogastroduodenoscopy and colonoscopy initially suggested ischaemic colitis. The patient's legs were treated symptomatically with topical steroids. He later developed acute large volume bloody diarrhoea that made him haemodynamically unstable. Punch biopsy of the skin was consistent with leucocytoclastic vasculitis and direct immunofluorescence demonstrated immunoglobulin A and C3 deposits consistent with Henoch-Schonlein purpura. The patient was treated with oral steroids. Bleeding stabilised and rash resolved. Steroids were successfully tapered. The patient was discharged on haemodialysis but ultimately this was able to be discontinued.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: IgA Vasculitis / Lower Extremity / Exanthema / Multiple Organ Failure Type of study: Diagnostic_studies Limits: Aged / Humans / Male Language: En Journal: BMJ Case Rep Year: 2018 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: IgA Vasculitis / Lower Extremity / Exanthema / Multiple Organ Failure Type of study: Diagnostic_studies Limits: Aged / Humans / Male Language: En Journal: BMJ Case Rep Year: 2018 Document type: Article Affiliation country: Country of publication: