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Double methylation of tRNA-U54 to 2'-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7.
Keller, Patrick; Freund, Isabel; Marchand, Virginie; Bec, Guillaume; Huang, Raven; Motorin, Yuri; Eigenbrod, Tatjana; Dalpke, Alexander; Helm, Mark.
Affiliation
  • Keller P; Institute of Pharmacy and Biochemistry, Johannes Gutenberg-University of Mainz, Staudingerweg 5, D-55128 Mainz, Germany.
  • Freund I; Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Marchand V; Next Generation Sequencing Platform, UMS2008 Ingénierie Biologie Santé en Lorraine (IBSLor), BioPôle de l'Université de Lorraine Campus Biologie-Santé, 9, avenue de la Forêt de Haye, CS 50184, 54505 Vandoeuvre-les-Nancy, France.
  • Bec G; Biophysics and Structural Biology Team, Unité Architecture et réactivité de l'ARN (UPR9002), Institut de Biologie Moléculaire et Cellulaire du CNRS, Université de Strasbourg, 15, rue René Descartes, F67084, Strasbourg cedex, France.
  • Huang R; Department of Biochemistry, Center for Biophysics & Computational Biology, University of Illinois at Urbana-Champaign, 411 Roger Adams Lab., 600 S. Mathews Ave. Urbana, IL 61801, USA.
  • Motorin Y; Laboratoire Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA) UMR7365 CNRS-UL, BioPôle de l'Université de Lorraine Campus Biologie-Santé, 9, avenue de la Forêt de Haye, CS 50184, 54505 Vandoeuvre-les-Nancy, France.
  • Eigenbrod T; Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Dalpke A; Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Helm M; Institute of Pharmacy and Biochemistry, Johannes Gutenberg-University of Mainz, Staudingerweg 5, D-55128 Mainz, Germany.
Nucleic Acids Res ; 46(18): 9764-9775, 2018 10 12.
Article in En | MEDLINE | ID: mdl-30102387
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Transfer / Nucleic Acids / Toll-Like Receptor 7 / Immunity, Innate Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2018 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Transfer / Nucleic Acids / Toll-Like Receptor 7 / Immunity, Innate Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2018 Document type: Article Affiliation country: