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KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma.
Ciesielski, Michael J; Bu, Yahao; Munich, Stephan A; Teegarden, Paola; Smolinski, Michael P; Clements, James L; Lau, Johnson Y N; Hangauer, David G; Fenstermaker, Robert A.
Affiliation
  • Ciesielski MJ; Department of Neurosurgery, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, 14263, USA.
  • Bu Y; Athenex, Inc., 1001 Main Street Suite 600, Buffalo, NY, 14203, USA.
  • Munich SA; Department of Neurosurgery, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, 14263, USA.
  • Teegarden P; Athenex, Inc., 1001 Main Street Suite 600, Buffalo, NY, 14203, USA.
  • Smolinski MP; Athenex, Inc., 1001 Main Street Suite 600, Buffalo, NY, 14203, USA.
  • Clements JL; Athenex, Inc., 1001 Main Street Suite 600, Buffalo, NY, 14203, USA.
  • Lau JYN; Athenex, Inc., 1001 Main Street Suite 600, Buffalo, NY, 14203, USA.
  • Hangauer DG; Athenex, Inc., 1001 Main Street Suite 600, Buffalo, NY, 14203, USA.
  • Fenstermaker RA; Department of Neurosurgery, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, 14263, USA. Robert.Fenstermaker@RoswellPark.org.
J Neurooncol ; 140(3): 519-527, 2018 Dec.
Article in En | MEDLINE | ID: mdl-30238350
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Brain Neoplasms / Morpholines / Glioblastoma / Src-Family Kinases / Tubulin Modulators / Acetamides / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: J Neurooncol Year: 2018 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Brain Neoplasms / Morpholines / Glioblastoma / Src-Family Kinases / Tubulin Modulators / Acetamides / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: J Neurooncol Year: 2018 Document type: Article Affiliation country: Country of publication: