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Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness.
Levy, Yotam; Ross, Jacob A; Niglas, Marili; Snetkov, Vladimir A; Lynham, Steven; Liao, Chen-Yu; Puckelwartz, Megan J; Hsu, Yueh-Mei; McNally, Elizabeth M; Alsheimer, Manfred; Harridge, Stephen Dr; Young, Stephen G; Fong, Loren G; Español, Yaiza; Lopez-Otin, Carlos; Kennedy, Brian K; Lowe, Dawn A; Ochala, Julien.
Affiliation
  • Levy Y; School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, and.
  • Ross JA; School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, and.
  • Niglas M; School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, and.
  • Snetkov VA; School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, and.
  • Lynham S; Proteomics Facility, Centre of Excellence for Mass Spectrometry, King's College London, London, United Kingdom.
  • Liao CY; Buck Institute for Research on Aging, Novato, California, USA.
  • Puckelwartz MJ; Center for Genetic Medicine, Northwestern University, Chicago, Illinois, USA.
  • Hsu YM; Buck Institute for Research on Aging, Novato, California, USA.
  • McNally EM; Center for Genetic Medicine, Northwestern University, Chicago, Illinois, USA.
  • Alsheimer M; Department of Cell and Developmental Biology, University of Würzburg, Würzburg, Germany.
  • Harridge SD; School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, and.
  • Young SG; Department of Medicine, University of California Los Angeles, Los Angeles, California, USA.
  • Fong LG; Department of Medicine, University of California Los Angeles, Los Angeles, California, USA.
  • Español Y; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain.
  • Lopez-Otin C; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain.
  • Kennedy BK; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Spain.
  • Lowe DA; Buck Institute for Research on Aging, Novato, California, USA.
  • Ochala J; Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
JCI Insight ; 3(19)2018 10 04.
Article in En | MEDLINE | ID: mdl-30282816
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Muscle Fibers, Skeletal / Aging, Premature / Lamin Type A / Muscle Strength Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2018 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Muscle Fibers, Skeletal / Aging, Premature / Lamin Type A / Muscle Strength Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2018 Document type: Article Country of publication: