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Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice.
Moritoki, Yuki; Tsuneyama, Koichi; Nakamura, Yuka; Kikuchi, Kentaro; Shiota, Akira; Ohsugi, Yoshiyuki; Lian, Zhe-Xiong; Zhang, Weici; Yang, Guo-Xiang; Ueki, Shigeharu; Takeda, Masahide; Omokawa, Ayumi; Saga, Tomoo; Saga, Akiko; Watanabe, Daisuke; Miura, Masahito; Ueno, Yoshiyuki; Leung, Patrick S C; Tanaka, Atsushi; Gershwin, M Eric; Hirokawa, Makoto.
Affiliation
  • Moritoki Y; Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
  • Tsuneyama K; Center for Medical Education and Training, Akita University Hospital, Akita, Japan.
  • Nakamura Y; SimTiki Simulation Center, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
  • Kikuchi K; Department of Pathology and Laboratory Medicine, Institute of Biomedical Science, Tokushima University Graduate School of Medicine, Tokushima, Japan.
  • Shiota A; Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
  • Ohsugi Y; Department of Fourth Internal Medicine, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
  • Lian ZX; Institute of Immunology, Co., Ltd., Tokyo, Japan.
  • Zhang W; Ohsugi BioPharma Consulting, Co., Ltd., Tokyo, Japan.
  • Yang GX; Chronic Disease Laboratory, Institutes for Life Sciences and School of Medicine, South China University of Technology, Guangzhou, China.
  • Ueki S; Division of Rheumatology, Allergy and Clinical Immunology, Genome and Biomedical Sciences Facility, University of California, Davis, Davis, CA, United States.
  • Takeda M; Division of Rheumatology, Allergy and Clinical Immunology, Genome and Biomedical Sciences Facility, University of California, Davis, Davis, CA, United States.
  • Omokawa A; Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
  • Saga T; Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
  • Saga A; Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
  • Watanabe D; Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
  • Miura M; Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
  • Ueno Y; Watanabe Internal Medicine Clinic, Noshiro, Japan.
  • Leung PSC; Department of Gastroenterology, Omagari Kosei Medical Center, Omagari, Japan.
  • Tanaka A; Department of Gastroenterology, Yamagata University Faculty of Medicine, Yamagata, Japan.
  • Gershwin ME; Division of Rheumatology, Allergy and Clinical Immunology, Genome and Biomedical Sciences Facility, University of California, Davis, Davis, CA, United States.
  • Hirokawa M; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Front Immunol ; 9: 2534, 2018.
Article in En | MEDLINE | ID: mdl-30450101
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / B-Lymphocytes / CD8-Positive T-Lymphocytes / Antibodies, Monoclonal, Humanized / Immunotherapy / Inflammation / Liver / Liver Cirrhosis, Biliary Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Front Immunol Year: 2018 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / B-Lymphocytes / CD8-Positive T-Lymphocytes / Antibodies, Monoclonal, Humanized / Immunotherapy / Inflammation / Liver / Liver Cirrhosis, Biliary Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Front Immunol Year: 2018 Document type: Article Affiliation country: Country of publication: