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Metformin increases antitumor activity of MEK inhibitor binimetinib in 2D and 3D models of human metastatic melanoma cells.
Ryabaya, Oxana; Prokofieva, Anastasia; Akasov, Roman; Khochenkov, Dmitry; Emelyanova, Marina; Burov, Sergey; Markvicheva, Elena; Inshakov, Andrey; Stepanova, Evgenia.
Affiliation
  • Ryabaya O; Department of Experimental Diagnostic and Tumor Therapy N.N. Blokhin National Medical Research Center for Oncology, 115478, 24 Kashirskoe shosse, Moscow, Russia. Electronic address: oxa2601@yandex.ru.
  • Prokofieva A; Department of Experimental Diagnostic and Tumor Therapy N.N. Blokhin National Medical Research Center for Oncology, 115478, 24 Kashirskoe shosse, Moscow, Russia. Electronic address: nastia29mal@mail.ru.
  • Akasov R; Institute of Molecular Medicine Sechenov First Moscow State Medical University, 119991, 8-2 Trubetskaya street, Moscow, Russia; Cytomed J.S.Co, Russia; Federal Scientific Research Center «Crystallography and Photonics¼ Russian Academy of Sciences, 117997, 17a Butlerova st, Moscow, Russia. Electronic
  • Khochenkov D; Department of Experimental Diagnostic and Tumor Therapy N.N. Blokhin National Medical Research Center for Oncology, 115478, 24 Kashirskoe shosse, Moscow, Russia. Electronic address: khochenkov@gmail.com.
  • Emelyanova M; Department of Biological Microchips Engelhardt Institute of Molecular Biology, 119991, 32 Vavilova street, Moscow, Russia. Electronic address: emel_marina@mail.ru.
  • Burov S; Cytomed J.S.Co, Russia. Electronic address: burov@hq.macro.ru.
  • Markvicheva E; Department of Biomaterials and Biotechnologies, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia. Electronic address: lemarkv@hotmail.com.
  • Inshakov A; Department of Experimental Diagnostic and Tumor Therapy N.N. Blokhin National Medical Research Center for Oncology, 115478, 24 Kashirskoe shosse, Moscow, Russia. Electronic address: an-inshakov@yandex.ru.
  • Stepanova E; Department of Experimental Diagnostic and Tumor Therapy N.N. Blokhin National Medical Research Center for Oncology, 115478, 24 Kashirskoe shosse, Moscow, Russia. Electronic address: stepanova.rosc@gmail.com.
Biomed Pharmacother ; 109: 2548-2560, 2019 Jan.
Article in En | MEDLINE | ID: mdl-30551515
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / MAP Kinase Kinase 1 / MAP Kinase Kinase 2 / Melanoma / Metformin Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2019 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / MAP Kinase Kinase 1 / MAP Kinase Kinase 2 / Melanoma / Metformin Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2019 Document type: Article Country of publication: