Bone and Joint Tissue Penetration of the <i>Staphylococcus</i>-Selective Antibiotic Afabicin in Patients Undergoing Elective Hip Replacement Surgery.

Menetrey, Annick; Janin, Annick; Pullman, John; Overcash, J Scott; Haouala, Amina; Leylavergne, François; Turbe, Laurent; Wittke, Frederick; Nicolas-Métral, Valérie

Bone and Joint Tissue Penetration of the Staphylococcus-Selective Antibiotic Afabicin in Patients Undergoing Elective Hip Replacement Surgery.

Menetrey, Annick; Janin, Annick; Pullman, John; Overcash, J Scott; Haouala, Amina; Leylavergne, François; Turbe, Laurent; Wittke, Frederick; Nicolas-Métral, Valérie.

Affiliation

Menetrey A; Debiopharm International SA, Lausanne, Switzerland annick.menetrey@debiopharm.com.
Janin A; Debiopharm International SA, Lausanne, Switzerland.
Pullman J; St. James Healthcare, SCL Health, Butte, Montana, USA.
Overcash JS; Sharp Grossmont Hospital, La Mesa, California, USA.
Haouala A; Debiopharm International SA, Lausanne, Switzerland.
Leylavergne F; Debiopharm International SA, Lausanne, Switzerland.
Turbe L; Atlanbio, Saint-Nazaire, France.
Wittke F; Debiopharm International SA, Lausanne, Switzerland.
Nicolas-Métral V; Debiopharm International SA, Lausanne, Switzerland.

Antimicrob Agents Chemother ; 63(3)2019 03.

Article in En | MEDLINE | ID: mdl-30559136

Subject(s)
Key words

Debio 1450; Staphylococcus aureus; afabicin; drug development; drug penetration; joint infections; osteomyelitis; pharmacokinetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcal Infections / Benzofurans / Prosthesis-Related Infections / Methicillin-Resistant Staphylococcus aureus / Anti-Bacterial Agents / Naphthyridines Type of study: Prognostic_studies Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2019 Document type: Article Affiliation country: Country of publication:

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